Cheap flights from Mexico City to Panama City from $361 MEX, NLU, TLC → PAC, PTY

Found recently, and the cheapest we hold

What have prices looked like?

Over 49 days, 24 Sept to 12 Nov, the cheapest return we saw each day was $334 to $491.

At $508, the cheapest return found recently is above that range.

Those were the prices on those days, not today's.

Could nearby dates be cheaper?

We hold no other 3-night return fares leaving within 3 days of 22 Mar 2027 to compare.

Every date we hold

94 fares on 5 departure dates

Which month looks cheapest?

December 2026 is the cheapest month — from $381.

Found recently, and the cheapest we hold

What have prices looked like?

Over 26 days, 25 Sept to 12 Nov, the cheapest one-way we saw each day was $196 to $361.

At $361, the cheapest one-way found recently is at the high end of that range.

26 days is a short history, so treat this range as an early guide.

Those were the prices on those days, not today's.

Could nearby dates be cheaper?

We hold no other one-way fares leaving within 3 days of 1 Jun 2027 to compare.

Every date we hold

5 fares on 1 departure dates

Return

Fares 30 to 59 days before departure were typically 13% lower than 0 to 6 days before departure.

From the cheapest return each day between 24 Sept and 12 Nov (49 days), grouped by how many days ahead the flight left; one adult in economy.

Each range covers different departure dates, so this compares typical fares, not the same trip priced twice.

Prices reflect recent searches — current fares may differ.

One-way

The cheapest fares were 60 to 89 days before departure.

From the cheapest one-way each day between 25 Sept and 12 Nov (26 days), grouped by how many days ahead the flight left; one adult in economy.

Each range covers different departure dates, so this compares typical fares, not the same trip priced twice.

Prices reflect recent searches — current fares may differ.

How much is a return flight from Mexico City to Panama City?

The cheapest return found recently is $508 with Copa Airlines, 22 Mar 2027 to 25 Mar 2027, found yesterday. The cheapest return we hold, of any age, is $381 with Copa Airlines, 10 Dec to 10 Dec, found 5 days ago. The cheapest return fare on each of 5 departure dates is usually $508 to $540.

How much is a one-way flight from Mexico City to Panama City?

The cheapest one-way found recently is $361 with Aeromexico, 1 Jun 2027, found 2 days ago. The cheapest one-way we hold, of any age, is $340 with avianca airlines, 1 Jun 2027, found 6 days ago.

What is the cheapest month to fly from Mexico City to Panama City?

December 2026 is the cheapest month for a return, from $381, 10 Dec to 10 Dec, found 5 days ago.

How far ahead should I book a flight from Mexico City to Panama City?

In 49 days of prices between 24 Sept and 12 Nov, return fares 30 to 59 days before departure were typically 13% lower than 0 to 6 days before departure. In 26 days of prices between 25 Sept and 12 Nov, one-way fares were cheapest 60 to 89 days before departure.

Is there a direct flight from Mexico City to Panama City?

Yes, the cheapest nonstop return found recently is $508 with Copa Airlines, 22 Mar 2027 to 25 Mar 2027, found yesterday. The cheapest nonstop one-way found recently is $361 with Aeromexico, 1 Jun 2027, found 2 days ago.

How long is the flight from Mexico City to Panama City?

The cheapest nonstop one-way found recently, with Aeromexico on 1 Jun 2027, takes 4 h from Benito Juarez International Airport (MEX) to Tocumen International Airport (PTY).

Which airlines have the cheapest flights from Mexico City to Panama City?

Between 29 Nov and 15 Jun 2027, Aeromexico has the cheapest return on 2 of the 5 departure dates we hold, Copa Airlines on 2 and avianca airlines on 1.